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Journal of Biomedicine and Biotechnology
Volume 2012 (2012), Article ID 175619, 6 pages
http://dx.doi.org/10.1155/2012/175619
Research Article

Tramadol Pretreatment Enhances Ketamine-Induced Antidepressant Effects and Increases Mammalian Target of Rapamycin in Rat Hippocampus and Prefrontal Cortex

1Department of Anesthesiology, School of Medicine, Jinling Hospital, Nanjing University, No. 305 East Zhongshan Road, Jiangsu Nanjing 210002, China
2Department of Anesthesiology, Affiliated Drum-Tower Hospital of Medical College of Nanjing University, No. 321 Zhongshan Road, Jiangsu Nanjing 210008, China
3The PLA 102nd Hospital and Mental Health Center of Military, No. 55 North Heping Road, Jiangsu Changzhou 213000, China

Received 14 January 2012; Revised 6 February 2012; Accepted 8 February 2012

Academic Editor: Daniel T. Monaghan

Copyright © 2012 Chun Yang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Chun Yang, Wen-Yuan Li, Hai-Yin Yu, et al., “Tramadol Pretreatment Enhances Ketamine-Induced Antidepressant Effects and Increases Mammalian Target of Rapamycin in Rat Hippocampus and Prefrontal Cortex,” Journal of Biomedicine and Biotechnology, vol. 2012, Article ID 175619, 6 pages, 2012. doi:10.1155/2012/175619