Tramadol Pretreatment Enhances Ketamine-Induced Antidepressant Effects and Increases Mammalian Target of Rapamycin in Rat Hippocampus and Prefrontal Cortex
Figure 4
The expression of p-mTOR in rat hippocampus . Ketamine administered at the 10 mg/kg significantly increased the expression of p-mTOR in rat hippocampus as compared with control (*), and tramadol pretreated at the dose of 5 mg/kg significantly increased the expression of p-mTOR as compared with ketamine administered alone (#).
