The Immunologic Injury Composite with Balloon Injury Leads to Dyslipidemia: A Robust Rabbit Model of Human Atherosclerosis and Vulnerable Plaque

Figure 4

Vulnerability plaque has been identified on CIB rabbit. (a) Representative aortic sections stained by Oil red O, trichrome, CD68 antibody and a SMC-specific antibody (magnification ×40). (b) Quantification revealed a significantly larger lipid core, collagen, SMA-positive area, and the density of macrophages (identified by CD 68 immunostaining) in CIB rabbits. Data are expressed as mean±SD, ^∗∗𝑃<0.01 compared with normal.

(a)

(b)