The Immunologic Injury Composite with Balloon Injury Leads to Dyslipidemia: A Robust Rabbit Model of Human Atherosclerosis and Vulnerable Plaque

<table>Analysis of biochemical measurements in two groups of rabbits. Serum level of IL-1, ox-LDL, NO, SOD, MDA, MCP-1, and TNF-<i>α</i> by using of enzyme-linked immunosorbent assay on week 0, 3, 6, 10. IL-1, interleukin-1; ox-LDL, oxidized LDL cholesterol; NO, nitric oxide; SOD, superoxide dismutase; MDA, malondialdehyde; MCP-1, monocyte chemoattractant protein-1; TNF-<i>α</i>, tumor necrosis factor-<i>α</i>. Data are expressed as <svg height="12.05" id="M25" style="vertical-align:-1.09097pt" version="1.1" viewbox="0 0 71.599998 12.05" width="71.599998" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,12.05)">
<g transform="translate(72,-62.36)">
<text transform="matrix(1,0,0,-1,-71.95,63.5)">
<tspan style="font-size: 12.50px; " x="0" y="0">m</tspan>
<tspan style="font-size: 12.50px; " x="9.727334" y="0">e</tspan>
<tspan style="font-size: 12.50px; " x="15.278666" y="0">a</tspan>
<tspan style="font-size: 12.50px; " x="20.829998" y="0">n</tspan>
<tspan style="font-size: 12.50px; " x="29.857164" y="0">±</tspan>
<tspan style="font-size: 12.50px; " x="41.197384" y="0">S</tspan>
<tspan style="font-size: 12.50px; " x="48.149052" y="0">D</tspan>
</text>
</g>
</g>
</svg>, <svg height="11.9" id="M26" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 62.487499 11.9" width="62.487499" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,11.9)">
<g transform="translate(72,-62.48)">
<text transform="matrix(1,0,0,-1,-71.95,67.83)">
<tspan style="font-size: 8.75px; " x="0" y="0">∗</tspan>
</text>
<text transform="matrix(1,0,0,-1,-66.87,62.83)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑃</tspan>
<tspan style="font-size: 12.50px; " x="10.890113" y="0">&lt;</tspan>
<tspan style="font-size: 12.50px; " x="22.930502" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="29.182001" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="32.307751" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="38.559254" y="0">5</tspan>
</text>
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</g>
</svg>, <svg height="11.9" id="M27" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 68.212502 11.9" width="68.212502" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,11.9)">
<g transform="translate(72,-62.48)">
<text transform="matrix(1,0,0,-1,-71.95,67.83)">
<tspan style="font-size: 8.75px; " x="0" y="0">∗</tspan>
<tspan style="font-size: 8.75px; " x="4.5772958" y="0">∗</tspan>
</text>
<text transform="matrix(1,0,0,-1,-62.3,62.83)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑃</tspan>
<tspan style="font-size: 12.50px; " x="10.890113" y="0">&lt;</tspan>
<tspan style="font-size: 12.50px; " x="22.930502" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="29.182001" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="32.307751" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="38.559254" y="0">1</tspan>
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</svg> compared with normal group.</table>

BioMed Research International

fig7

Figure 7

Figure 7: The Immunologic Injury Composite with Balloon Injury Leads to Dyslipidemia: A Robust Rabbit Model of Human Atherosclerosis and Vulnerable Plaque 

Figure 7 | The Immunologic Injury Composite with Balloon Injury Leads to Dyslipidemia: A Robust Rabbit Model of Human Atherosclerosis and Vulnerable Plaque 