Assessment of the Immune Responses Induced in Cattle after Inoculation of a Mycobacterium bovis Strain Deleted in Two mce2 Genes

Figure 2

Percentages of lymphocyte cell subsets CD4+ (a) and CD8+ (b) expressing CD25 of PBMCs from animals inoculated with either MbΔmce2 (𝑛=4, triangle) or NCTC 10772 (𝑛=3, circle) stimulated with PPDB (black) or PBS (white) at different time points. Data were analyzed using the Wilcoxon matched pair test for cells with and without PPDB stimulation (*statistically significant 𝑃<0.05 and **statistically significant 𝑃<0.01). The means ± SEM are indicated.

(a)

(b)