Figure 4: Fibrinogen deposition in arteries from different groups with immunohistochemistry. Areas of positive fibrinogen deposition are shown in brown. The representative photographs of immunohistochemistry from different groups are shown. In the control group (a), the deposition of fibrinogen in the intima was minimum, while in the HFD group (b), there was much more fibrinogen deposition in the intima. In the rosuvastatin group (c), there was less fibrinogen deposition in the intima compared with HFD group. In the atRA group (d), the fibrinogen deposition was significantly less in comparison with either HFD or rosuvastatin group (magnification ×400).