In Vivo Visualization of Heterogeneous Intratumoral Distribution of Hypoxia-Inducible Factor-1𝜶 Activity by the Fusion of High-Resolution SPECT and Morphological Imaging Tests

Figure 1

Biodistribution of ¹²⁵I-POS in FM3A-bearing mice.  Administration dose of ¹²⁵I-POS 2.0 MBq, POS: 30 μg, tumor weight: 0.3–2.3 g, tumor uptake 4.3% AD/g, T/B: 13.1% (𝑛=5).