Pharmacokinetic Models for FcRn-Mediated IgG Disposition
Figure 4
Simulated PK profiles using the mouse cutoff model. All mice receive 8 mg/kg 7E3 with or without concomitant 1 g/kg IVIG in either FcRn WT or KO mice. Plasma and peripheral concentrations of 7E3, IVIG IgG, and endogenous IgG are plotted.
