Table of Contents Author Guidelines Submit a Manuscript
Journal of Biomedicine and Biotechnology
Volume 2012, Article ID 286216, 6 pages
http://dx.doi.org/10.1155/2012/286216
Research Article

Effects of Saponins against Clinical E. coli Strains and Eukaryotic Cell Line

1Department of Microbiology, Institute of Biology, Jan Kochanowski University in Kielce, ul. Świętokrzyska 15, 25-406 Kielce, Poland
2Department of Radiobiology and Immunology, Jan Kochanowski University in Kielce, ul. Świętokrzyska 15, 25-406 Kielce, Poland
3Center for Biological Densitometry and Radiobiology, Institute of Chemistry and Nuclear Technology, ul. Dorodna 16, 03-195 Warsaw, Poland

Received 12 September 2011; Accepted 22 November 2011

Academic Editor: Celina Janion

Copyright © 2012 Michał Arabski et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. G. Sparg, M. E. Light, and J. Van Staden, “Biological activities and distribution of plant saponins,” Journal of Ethnopharmacology, vol. 94, no. 2-3, pp. 219–243, 2004. View at Publisher · View at Google Scholar · View at Scopus
  2. Y. M. Leung, Y. J. Ou, C. Y. Kwan, and T. T. Loh, “Specific interaction between tetrandrine and Quillaja saponins in promoting permeabilization of plasma membrane in human leukemic HL-60 cells,” Biochimica et Biophysica Acta, vol. 1325, no. 2, pp. 318–328, 1997. View at Publisher · View at Google Scholar · View at Scopus
  3. S. Sen, H. P. S. Makkar, S. Muetzel, and K. Becker, “Effect of Quillaja saponaria saponins and Yucca schidigera plant extract on growth of Escherichia coli,” Letters in Applied Microbiology, vol. 27, no. 1, pp. 35–38, 1998. View at Publisher · View at Google Scholar · View at Scopus
  4. C. Bachran, M. Sutherland, I. Heisler, P. Hebestreit, M. F. Melzig, and H. Fuchs, “The saponin-mediated enhanced uptake of targeted saporin-based drugs is strongly dependent on the saponin structure,” Experimental Biology and Medicine, vol. 231, no. 4, pp. 412–420, 2006. View at Google Scholar · View at Scopus
  5. M. Chwalek, N. Lalun, H. Bobichon, K. Plé, and L. Voutquenne-Nazabadioko, “Structure-activity relationships of some hederagenin diglycosides: haemolysis, cytotoxicity and apoptosis induction,” Biochimica et Biophysica Acta, vol. 1760, no. 9, pp. 1418–1427, 2006. View at Publisher · View at Google Scholar · View at Scopus
  6. H. Gögelein and A. Hüby, “Interaction of saponin and digitonin with black lipid membranes and lipid monolayers,” Biochimica et Biophysica Acta, vol. 773, no. 1, pp. 32–38, 1984. View at Google Scholar
  7. H. Myszka, D. Bednarczyk, M. Najder, and W. S. Kaca, “Synthesis and induction of apoptosis in B cell chronic leukemia by diosgenyl 2-amino-2-deoxy-β-D-glucopyranoside hydrochloride and its derivatives,” Carbohydrate Research, vol. 338, no. 2, pp. 133–141, 2003. View at Publisher · View at Google Scholar · View at Scopus
  8. E. Baumann, G. Stoya, A. Völkner, W. Richter, C. Lemke, and W. Linss, “Hemolysis of human erythrocytes with saponin affects the membrane structure,” Acta Histochemica, vol. 102, no. 1, pp. 21–35, 2000. View at Google Scholar · View at Scopus
  9. R. Segal, P. Shatkovsky, and I. Milo Goldzweig, “On the mechanism of saponin hemolysis. I. Hydrolysis of the glycosidic bond,” Biochemical Pharmacology, vol. 23, no. 5, pp. 973–981, 1974. View at Publisher · View at Google Scholar · View at Scopus
  10. W. P. Winter, “Mechanism of saponin induced red cell hemolysis: evidence for the involvement of aquaporin CHIP28,” Blood, vol. 84, supplement 1–10, abstract 445, 1994. View at Google Scholar
  11. M. Arabski, S. Wasik, K. Dworecki, and W. Kaca, “Laser interferometric and cultivation methods for measurement of colistin/ampicilin and saponin interactions with smooth and rough of Proteus mirabilis lipopolysaccharides and cells,” Journal of Microbiological Methods, vol. 77, no. 2, pp. 178–183, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. S. O'Flaherty, R. P. Ross, and A. Coffey, “Bacteriophage and their lysins for elimination of infectious bacteria: Review article,” FEMS Microbiology Reviews, vol. 33, no. 4, pp. 801–819, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. B. Montdargent and D. Letourneur, “Toward new biomaterials,” Infection Control and Hospital Epidemiology, vol. 21, no. 6, pp. 404–410, 2000. View at Google Scholar · View at Scopus
  14. L. Mamelli, S. Petit, J. Chevalier et al., “New antibiotic molecules: bypassing the membrane barrier of gram negative bacteria increases the activity of peptide deformylase inhibitors,” PLoS ONE, vol. 4, no. 7, article e6443, 2009. View at Publisher · View at Google Scholar · View at Scopus
  15. I. Majsterek, M. Arabski, A. Czechowska et al., “Imatinib (STI571) inhibits DNA repair in human leukemia oncogenic tyrosine kinase-expressing cells,” Zeitschrift fur Naturforschung C, vol. 61, no. 11-12, pp. 896–902, 2006. View at Google Scholar · View at Scopus
  16. Z. Darzynkiewicz, Current Protocols in Cell Biology, John Wiley & Sons, 2003.
  17. M. Arabski, K. Gwoździnski, B. Sudak, and W. Kaca, “Effects of Proteus mirabilis lipopolysaccharides with different O-polysaccharide structures on the plasma membrane of human erythrocytes,” Zeitschrift fur Naturforschung C, vol. 63, no. 5-6, pp. 460–468, 2008. View at Google Scholar · View at Scopus
  18. J. Sambrook and D. W. Russell, Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory Press, New York, NY, USA, 3rd edition, 1989.
  19. M. C. Jacob, M. Favre, and J. C. Bensa, “Membrane cell permeabilisation with saponin and multiparametric analysis by flow cytometry,” Cytometry, vol. 12, no. 6, pp. 550–558, 1991. View at Google Scholar · View at Scopus
  20. D. Pelah, Z. Abramovich, A. Markus, and Z. Wiesman, “The use of commercial saponin from Quillaja saponaria bark as a natural larvicidal agent against Aedes aegypti and Culex pipiens,” Journal of Ethnopharmacology, vol. 81, no. 3, pp. 407–409, 2002. View at Publisher · View at Google Scholar · View at Scopus