Effects of Saponins against Clinical E. coli Strains and Eukaryotic Cell Line

Table 1

Percentage of early and late apoptotic and necrotic CHO-K1 cells following treatment with saponin measured by flow cytometry; mean of three experiments ± SD. IP: propidium iodide.

Saponin (μg/mL)	Normal cells (Annexin−/IP−)	Apoptosis		Necrosis (Annexin−/IP+)
		Early (Annexin+/IP−)	Late (Annexin+/IP+)
0	96.08±0.07	0.07±0.06	2.53±0.06	0.69±0.06
12	85.75±0.62	5.99±0.33	6.21±0.19	2.06±0.13
25	79.73±2.52	18.67±2.49	1.89±0.04	0.70±0.04
50	64.59±0.32	30.88±0.10	2.09±0.16	2.52±0.17