Expression of GA733-Fc Fusion Protein as a Vaccine Candidate for Colorectal Cancer in Transgenic Plants

<table>Immune response of mice injected with plant-derived GA733-FcK (GA733<sup>P</sup>-FcK) and mammalian-derived GA733-Fc (GA733<sup>M</sup>-Fc, the recombinant human EpCAM/TROP-1 Fc chimera). SW480, SW1116, and SW620 are human colorectal cancer cell lines; MCF-7 is human breast cancer cell line. <svg height="10.325" id="M1" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 13.4125 10.325" width="13.4125" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,10.325)">
<g transform="translate(72,-63.74)">
<text transform="matrix(1,0,0,-1,-71.95,63.79)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑋</tspan>
</text>
</g>
</g>
</svg>-axis, serum dilution (1/100X); <svg height="10.325" id="M2" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 11.6125 10.325" width="11.6125" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,10.325)">
<g transform="translate(72,-63.74)">
<text transform="matrix(1,0,0,-1,-71.95,63.79)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑌</tspan>
</text>
</g>
</g>
</svg>-axis, OD 450 nm.</table>

BioMed Research International

fig9

Figure 9

Figure 9: Expression of GA733-Fc Fusion Protein as a Vaccine Candidate for Colorectal Cancer in Transgenic Plants 