The Annexin A2/S100A10 System in Health and Disease: Emerging Paradigms
Figure 3
A2-expressing neovessels in oxygen-induced retinopathy in the mouse. Sections through retinas of wild type mice maintained in room air (a) or treated for five days with 75% oxygen to initiate oxygen-induced retinopathy (b) were stained with an endothelial cell-specific lectin (isolectin B4—green), 4′,6-diamidino-2-phenylindole for nuclei (DAPI—blue), and anti-A2 (red) as described [32]. Note A2-positive neovascular tufts arrayed at the inner limiting membrane of the oxygen-treated retina (b, arrowheads) versus control (a, arrowheads).
