Figure 4: Effect of Ad-siTLR4 transfection on the expression of proinflammatory cytokines in the lung of ALI rats. The TNF-α (a) and IL-1β (b) were determined by ELISA at 4 h after LPS administration. Data were expressed as fold change when compared with saline-treated animals. 𝑃 < 0 . 0 5 versus Ad-EGFP group, # 𝑃 < 0 . 0 5 versus control group.