Small Interference RNA Targeting TLR4 Gene Effectively Attenuates Pulmonary Inflammation in a Rat Model

Figure 4

Effect of Ad-siTLR4 transfection on the expression of proinflammatory cytokines in the lung of ALI rats. The TNF-α (a) and IL-1β (b) were determined by ELISA at 4 h after LPS administration. Data were expressed as fold change when compared with saline-treated animals. ^∗𝑃<0.05 versus Ad-EGFP group, ^#𝑃<0.05 versus control group.

(a)

(b)