Transverse 123I-β-CIT images. (a) The image from a healthy control. (b) in PD patient the uptake is markedly reduced, with putamen more affected than caudate, and the right striatum (opposite to the side of more severe symptoms) showing the largest dopamine transporter (DAT) loss. (c) In MSA-striatonigral degeneration (MSA-SND) patient, the uptake is significantly reduced in both caudate and putamen and indicates more symmetric loss of DAT. (d) In the MSA-Shy-Drager syndrome (SDS) patient, the uptake is also significantly reduced, with putamen more affected than caudate; the loss of DAT appears to be symmetric [64].
