Figure 4: Histopathological aspects of deep second-degree thermal burns. Masson’s trichrome staining. 100x Magnification. (a) Animal showing thin crust and epithelial tissue with complete destruction of dermis and epidermis and hypodermis maintenance at the 7th day after the thermal lesion induction. (b) Animal at day 14, with crust and tissue reepithelialization, showing collagen, not modeled and slight fibrosis. (c) Animal at day 21, tissue repithelialization showing intense fibroblastic proliferation with the presence of dense collagen, not modeled and moderate fibrosis. (d) Animal at day 28, with incomplete tissue repithelialization, moderate fibroblastic proliferation, presence of modeled dense collagen mesh, and moderate fibrosis.