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Journal of Biomedicine and Biotechnology
Volume 2012, Article ID 484869, 8 pages
http://dx.doi.org/10.1155/2012/484869
Research Article

Effect of Heat Exposure on Gene Expression of Feed Intake Regulatory Peptides in Laying Hens

1Department of Animal Science, Shandong Agricultural University, Taian, Shandong 271018, China
2Department of Animal Science, Faculty of Agriculture, University of Kurdistan, Sanandaj 66177-15175, Iran

Received 6 December 2011; Revised 27 January 2012; Accepted 16 February 2012

Academic Editor: Dominic Fan

Copyright © 2012 Zhigang Song et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The aim of this paper was to investigate the effect of heat stress on the regulation of appetite-associated genes in laying hens. Forty eight laying hens were randomly divided into two circumstances: high (31 ± 1.5°C; relative humidity, 82.0 ± 2.2%) or normal (20 ± 2°C, control; relative humidity, 60.1 ± 4.5%) ambient environment. Heat stress decreased body weight gain ( 𝑃 < 0 . 0 1 ), feed intake ( 𝑃 < 0 . 0 1 ), laying rate ( 𝑃 < 0 . 0 5 ), average egg mass ( 𝑃 < 0 . 0 1 ), egg production ( 𝑃 < 0 . 0 1 ), shell thickness ( 𝑃 < 0 . 0 1 ), and feed efficiency ( 𝑃 < 0 . 0 5 ). High ambient temperature decreased plasma uric acid ( 𝑃 < 0 . 0 5 ). Heat stress significantly increased mRNA levels of ghrelin and cocaine- and amphetamine-regulated transcript ( 𝑃 < 0 . 0 5 ) and decreased mRNA levels of cholecystokinin ( 𝑃 < 0 . 0 5 ) in the hypothalamus. Heat stress significantly increased ( 𝑃 < 0 . 0 5 ) mRNA levels of ghrelin in the glandular stomach and jejunum but significantly decreased ( 𝑃 < 0 . 0 5 ) mRNA levels of cholecystokinin in the duodenum and jejunum. In conclusion, heat stress plays a unique role in some special neuropeptides (e.g., ghrelin, cocaine- and amphetamine-regulated transcript, and cholecystokinin), which might participate in the regulation of feed intake in laying hens under high ambient temperature.