PET/CT Imaging in Mouse Models of Myocardial Ischemia

Table 2

Principal characteristics of PET tracers for cardiovascular imaging.

Tracer	Production	Half-life	Extraction	Myocardial uptake mechanism
^13N-ammonia	Cyclotron	10 min	80%	Diffusion/metabolic trapping (perfusion)
^82Rubidium	Generator	78 sec	50–60%	Na/K-ATPase (perfusion)
^15O-water	Cyclotron	2.1 min	100%	Free diffusion (perfusion)
F-18 FDG	Cyclotron	110 min	1–3%	Glucose transport/hexokinase (viability)

PET: positron emission tomography; Na/K-ATPase: sodium/potassium-ATPase; FDG: fluorodeoxyglucose.