A Novel Antihepatitis Drug, Bicyclol, Prevents Liver Carcinogenesis in Diethylnitrosamine-Initiated and Phenobarbital-Promoted Mice Tumor Model

Figure 6

Expression of PCNA in the control and experimental groups at week 20. (a) Representative microscopic pictures of PCNA-stained liver sections by immunohistochemical analysis (100×) and quantification of the immunostained section of PCNA. ^##𝑃<0.01 compared with the control group; *𝑃<0.05, **𝑃<0.01 compared with the DEN/PB model group. (b) Western blot assay of PCNA and the quantitative results obtained by measuring the optical density of each band and expressed as the ratio of each targeted protein and beta-actin. Average values of 3 separate experiments along with the standard deviations are shown. ^##𝑃<0.01 compared with the control group; *𝑃<0.05 compared with the DEN/PB model group.

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