Inhibition of Streptococcus gordonii Metabolic Activity in Biofilm by Cranberry Juice High-Molecular-Weight Component

Table 2

Effect of cranberry NDM on preformed S. gordonii biofilm.

NDM concentration (μg/mL)	Metabolic activity	Biofilm mass
0 (control)	2.21±0.3	2.36±0.41
2.5	2.14±0.18	2.33±0.33
5.0	2.24±0.22	2.39±0.27
7.5	2.06±0.4	2.35±0.44
10	1.96±0.33	2.41±0.31
20	1.84±0.59	2.34±0.41
25	1.97±1.1	2.36±0.29
50	1.86±0.69	2.39±0.3
100	1.08±0.44	2.35±0.28

Bacterial biofilm prepared as described previously was treated with varying concentrations of NDM (2.5 μg/mL to 100 μg/mL) for 60 minutes and 4 hours. The metabolic activity was determined by XTT assay and the biofilm mass determined by the crystal violet staining.