Improvement of Coenzyme Q10 Production: Mutagenesis Induced by High Hydrostatic Pressure Treatment and Optimization of Fermentation Conditions

Table 5

Effect of complex nitrogen sources on DCW and CoQ10 production by PK38 with batch culture.

CSP + (NH4)2SO4 (g/L)	DCW (g/L)	CoQ10 production (mg/L)	Specific CoQ10 content (mg/g-DCW)
20+0	7.16 + 0.116^d	17.65 + 0.098^d	2.466 + 0.017^c
20+5	6.73 + 0.139^f	16.17 + 0.091^f	2.403 + 0.010^c
20+10	6.92 + 0.097^e	17.08 + 0.082^e	2.467 + 0.027^c
20+15	7.13 + 0.067^d	17.60 + 0.115^d	2.469 + 0.031^c
30+0	7.46 + 0.095^c	18.92 + 0.146^c	2.536 + 0.047^b
30+5	7.65 + 0.107^b	19.40 + 0.284^b	2.537 + 0.068^b
30+10	7.86 + 0.090^a	20.62 + 0.121^a	2.624 + 0.032^a
30+15	7.60 + 0.512^b	18.54 + 0.085^c	2.439 + 0.162^c

Data are shown as mean ± SD (𝑛=3). Means with the same letter are not significantly different as indicated by Duncan’s multiple range test (P < 0.05).