Research Article

BMP9-Induced Osteogenetic Differentiation and Bone Formation of Muscle-Derived Stem Cells

Figure 2

Potentiation of BMP-induced early osteogenetic marker ALP activity in muscle-derived stem cells. (a) ALP staining in MDSCs. MDSCs were infected with AdBMP9, AdBMP2, and Ad-GFP. ALP staining was done at the indicated time points. ALP expression induced by BMP9 in MDSCs was shown higher than other groups. (b) BMP-induced ALP activity in MDSCs. MDSCs were infected with AdBMP9, AdBMP2, and Ad-GFP. ALP activity was measured at the indicated time points. Each assay condition was dose in triplicate. ALP activities induced by BMP9 in MDSCs were significantly higher in indicated time points ( 𝑃 < 0 . 0 0 1 ).
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(a)
610952.fig.002b
(b)