BioMed Research International / 2012 / Article / Tab 1

Research Article

Synergistic Antibacterial Effect between Silibinin and Antibiotics in Oral Bacteria

Table 1

Antibacterial activity of silibinin and antibiotics in oral bacteria.

SamplesSilibinin (μg/mL)AmpicillinGentamicin
MIC50<MIC90<MIC/MBCMIC/MBC (μg/mL)

S. mutans ATCC 2517510.050.20.2/0.40.125/0.58/16
S. sanguinis ATCC 105560.10.40.4/0.40.5/164/64
S. sobrinus ATCC 276070.10.40.4/0.80.5/14/8
S. ratti KCTC 329420.20.80.8/0.80.5/116/32
S. criceti KCTC 32920.20.80.8/1.61/28/16
S. anginosus ATCC 314120.10.80.8/1.61/232/32
S. gordonii ATCC 105580.0250.10.1/0.20.5/132/32
A. actinomycetemcomitans ATCC 437170.41.61.6/3.264/644/8
F. nucleatum ATCC 511900.43.23.2/6.42/42/4
P. intermedia ATCC 490490.41.61.6/3.24/816/32
P. gingivalis ATCC 332770.10.40.4/0.80.5/1256/512

1American Type Culture Collection (ATCC).
2Korean collection for type cultures (KCTC).

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