|
| | endogenous ligands | exogenous ligand |
|
| PPAR | Unsaturated fatty acids (oleic, palmitoleic, linoleic, arachidonic acid) | Hypolipidemic drugs (bezafibrate, clofibrate, ciprofibrate, fenofibrate, gemfibrozil, nafenopin, WY-14643) |
| Saturated fatty acids (palmitoic and stearic acid) | Phytanic acid |
| 5, 6-, 8, 9-, 11, 12-, 14, 15-eet | Nsaids (indomethacin) |
| Hydroperoxyeicosatetraenoic acids (hetes) | Dehydroxyepiandrosterone (DHEA) |
| 20, 14, 15-heet | Phtalates |
| Prostaglandins (PGD2, PGD1) | Anticonvulsants (valproic acid, phenobarbital) |
| Leucotriene B4 (LTB4) | Telmisartan |
| Vldl | Phytol |
| | Perfluorinated alkyl and sulfonyl acid comp. (pfoa, pfna, pfos) |
| | Oxirane compounds |
| | Etya |
| | Epoxyisoprostane |
| | Drf-2519 |
| | Bm 17.0744 |
| | Benz[a]anthracene |
| | Di- and trichloroacetic acid |
| | Mk-886* |
|
| PPAR | Mono-and polyunsaturated fatty acids | Tetradecylthioacetic acid |
| Saturated fatty acids | Hypolipidemic drugs (WY-14643, bezafibrate) |
| Prostaglandins (PGA1, PGD1, PGD2) | Valproic acid |
| 13-S-hydroxyoctadecadienoic acid (13-S-HODE) | Benz[a]anthracene |
| 4-hydroxynonenol (4-HNE) | Treprostinil sodium |
| VLDL, oxldl | Gw-501516 |
| | Sulindac sulfide* |
|
| PPAR | Unsaturated fatty acids (linoleic, linolenic, arachidonic, eisosapentateonic acid) | Thiazolidinediones (e.g., ciglitazone, pioglitazone, rosiglitazone, troglitazone) |
9-s-hode, 13-s-hode
15-s-hete, 5-s-hete, 12-s-hete | Nsaids (indomethacin, diclofenac, oxaprozin, zaltoprofen, ibuprofen, nimesulide, sulindac sulfide*)
Hypolipidemic drugs (bezafibrate, WY-14643, atorvastin) |
| Lysophosphatidic acid | Phtalates (MEHD, DEPH) |
| Hexadecylazelaicphosphatidylcholine | Bisphenol A diglicidyl ether |
| Prostaglandins (PGD1, PGD2, PGA1) | Natural (plant) phenols (genistein, curcumin, resveratol) |
| Nitroalkane derivate of linoleic acid | Telmisartan |
| Oxldl | Jtp-426467 |
| | Pemoline |
| | Phenylacetate |
| | Dhea |
| | LY171883 |
| | 2-bromopalmitate |
| | antidiabetic drugs (glimepiride, tolbutamide, chlorpropamide, gliclazide, glibenclamide, SR-202) |
| | F-L-Leu |
| | abietic acid |
| | organotin compounds tributyl- and triphenyltin |
| | perfluorooctanic acid (PFOA) |
| | T0070907* |
| | | GW9662* |
|
