BioMed Research International / 2012 / Article / Fig 2

Research Article

Alterations in Cell Cycle and Induction of Apoptotic Cell Death in Breast Cancer Cells Treated with α-Mangostin Extracted from Mangosteen Pericarp

Figure 2

Caspase activity of MDA-MB231 cells after treatment with α-mangostin. Caspase activity was evaluated by luminescence assay. Activity of caspase-3, caspase-8, and caspase-9, but not caspase-4, was significantly elevated in MDA-MB231 cells treated with 20 μM α-mangostin for 24 h (** 𝑃 < 0 . 0 1 ). Data are presented as mean ± SD. Five samples from control and α -mangostin-treated cells were used for measurement of caspase activity.

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