Insulin Resistance in Patients with Chronic Kidney Disease

Table 1

Clinical studies assessing IR in healthy controls, CKD patients, and patients receiving PD, HD, or kidney transplantation (KT).

Patients	𝑛	GDR (mg/kg/min)		HOMA index
Controls [38]	10	9.93±1.33		1.85–1.95
CKD [12]	29^a	6.91±2.46		2.24±1.06
Before Tx	After Tx	Before KT	After KT
With PD [37]	9^a	6.35±1.65	8.18±1.76
With HD [37]	10^a	6.53±1.84	9.74±2.88
1 M after KT [39]	34	3.05±2.72	1.67±1.25
6 M after KT [39]	34	3.05±2.72	2.32±2.83

CKD: chronic kidney disease; GDR: glucose disposal rate; HOMA: homeostasis model assessment for insulin resistance; ESRD: end stage renal disease; CAPD: continuous ambulatory PD; Tx: dialysis treatment; KT: kidney transplantation.
^aNondiabetic.