Protection of SH-SY5Y Neuronal Cells from Glutamate-Induced Apoptosis by 3,𝟔^′-Disinapoyl Sucrose, a Bioactive Compound Isolated from Radix Polygala

Table 1

Effect of DISS on Bax and Bcl-2 expression in SH-SY5Y cells after Glu exposure. β-actin was used as an internal control. Results are from three independent experiments.

	Control	Glu	Glu + DISS
		(8 mM)	(8 mM + 0.6 μmol/L)	(8 mM + 6 μmol/L)	(8 mM + 60 μmol/L)
Bax	1 ± 0.249	2.317 ± 0.280^##	2.081 ± 0.316	1.921 ± 0.458	1.597 ± 0.351**
Bcl-2	1 ± 0.109	0.467 ± 0.025^##	0.631 ± 0.018	0.743 ± 0.028	0.825 ± 0.016**

^##𝑃<0.01, compared with normal cultures; *𝑃<0.05, **𝑃<0.01 compared with Glu alone group.