Genistein Attenuates Vascular Endothelial Impairment in Ovariectomized Hyperhomocysteinemic Rats

<table>Alterations of plasma ET-1 levels after 12 wk different treatment. There was a significant increase of plasma ET-1 levels in ovariectomized HHcy rats. Supplementation with genistein could significantly lower the elevated Hcy levels. The results shown are mean ± SEM, <svg height="11.125" id="M29" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 36.237499 11.125" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> values were obtained by one-way ANOVA analysis. <svg height="13.95" id="M31" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 88.449997 13.95" width="88.449997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus Met; <svg height="15.775" id="M32" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 91.662498 15.775" width="91.662498" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus OVX + Met. </table>

BioMed Research International

fig6

Figure 6

Figure 6: Genistein Attenuates Vascular Endothelial Impairment in Ovariectomized Hyperhomocysteinemic Rats 