A Laccase with Antiproliferative and HIV-I Reverse Transcriptase Inhibitory Activities from the Mycorrhizal Fungus Agaricus placomyces

Table 3

Effect of metals and chemical reagents on the activity of A. placomyces laccase.

Metal ion	Relative activity (% of control)
	1.25 mM	2.5 mM	5.0 mM
K^+	93	92	91
Ca^2+	105	108	106
Cu^2+	58	65	71
Hg^2+	45	34	25
Mg^2+	105	99	99
Mn^2+	105	108	109
Pb^2+	52	55	56
Zn^2+	96	91	86
Al^3+	157	114	106
Fe^3+	68	60	47
EDTA	61	47	32

Laccase activity in the absence of chemical reagents was regarded as 100%.