Gecko Crude Peptides Induce Apoptosis in Human Liver Carcinoma Cells In Vitro and Exert Antitumor Activity in a Mouse Ascites H22 Xenograft Model

Table 1

Inhibition effect of Gecko-contained serum on HepG2 by MTT assay (mean ± SD, 𝑛=12).

Groups	Dose	24 h		48 h		72 h
	mg/mL	A	IR%	A	IR%	A	IR%
NS		0.42 ± 0.12	—	0.63 ± 0.02	—	0.95 ± 0.10	—
5-FU	1.3	0.20 ± 0.03*	53	0.14 ± 0.04*	77	0.07 ± 0.02**	92
GCPs	3	0.16 ± 0.06*	63	0.13 ± 0.03**	76	0.08 ± 0.10**	91
	1.5	0.24 ± 0.01*	42	0.26 ± 0.01**	57	0.27 ± 0.04**	78
	1	0.29 ± 0.02*	30	0.31 ± 0.03**	46	0.38 ± 0.06**	69
	0.75	0.32 ± 0.02*	23	0.37 ± 0.04**	31	0.39 ± 0.04**	58
	0.375	0.37 ± 0.02*	12	0.40 ± 0.02	25	0.45 ± 0.01**	43

* P < 0.05, **P < 0.01 versus control.