Research Article
Gecko Crude Peptides Induce Apoptosis in Human Liver Carcinoma Cells In Vitro and Exert Antitumor Activity in a Mouse Ascites H22 Xenograft Model
Table 3
Influence of Gecko on immune organs of transplanted H22 in mice (mean ± SD, ).
| Groups | Dosage (mg/kg) | Body weight (g) | White blood cell count (×109/L) | Spleen index (mg/10 g) | Thymus index (mg/10 g) |
| NS | 0 | 29.35 ± 3.2 | 7.86 ± 2.1 | 81.3 ± 12.5 | 14.7 ± 0.5 | ADR | 2 | 23.18 ± 3.6** | 6.04 ± 2.3 | 65.3 ± 11. 8 | 9.4 ± 0.4** | GCPs (H) | 80 | 26.13 ± 2.5* | 9.88 ± 0.8* | 117.1 ± 10.6* | 21.6 ± 0.4** | GCPs (M) | 40 | 26.71 ± 1.8 | 8.11 ± 3.16 | 99.8 ± 15.4 | 20.9 ± 0.7** | GCPs (L) | 20 | 27.68 ± 2.7 | 7.06 ± 1.64 | 92.7 ± 11.6 | 17.5 ± 0.6* |
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*
P < 0.05, **P < 0.01 versus control.
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