Research Article

Gecko Crude Peptides Induce Apoptosis in Human Liver Carcinoma Cells In Vitro and Exert Antitumor Activity in a Mouse Ascites H22 Xenograft Model

Table 3

Influence of Gecko on immune organs of transplanted H22 in mice (mean ± SD, 𝑛 = 1 0 ).

GroupsDosage
(mg/kg)
Body weight
(g)
White blood cell count
(×109/L)
Spleen index
(mg/10 g)
Thymus index
(mg/10 g)

NS029.35 ± 3.27.86 ± 2.181.3 ± 12.514.7 ± 0.5
ADR223.18 ± 3.6**6.04 ± 2.365.3 ± 11. 89.4 ± 0.4**
GCPs (H)8026.13 ± 2.5*9.88 ± 0.8*117.1 ± 10.6*21.6 ± 0.4**
GCPs (M)4026.71 ± 1.88.11 ± 3.1699.8 ± 15.420.9 ± 0.7**
GCPs (L)2027.68 ± 2.77.06 ± 1.6492.7 ± 11.617.5 ± 0.6*

* P < 0.05, **P < 0.01 versus control.