Aberrant Expression of N-Methylpurine-DNA Glycosylase Influences Patient Survival in Malignant Gliomas

<table>Expression of MPG protein in glioma and nonneoplastic brain tissues by Western blot analysis. (a) MPG protein expression levels in glioma and nonneoplastic brain tissues. (b) MPG expression levels in glioma with different WHO grades. (c) MPG expression levels in nonneoplastic brain tissues and glioma with different WHO grades. “N” refers to nonneoplastic brain tissues; “Ca” refers to glioma tissues; “Ca_I”~“Ca_IV” refer to glioma tissues with WHO grade I~IV. <i>β</i>-actin was used as a control for equal protein loading. Values are means ±SD. <svg height="11.9" id="M11" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 62.487499 11.9" width="62.487499" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,11.9)">
<g transform="translate(72,-62.48)">
<text transform="matrix(1,0,0,-1,-71.95,67.83)">
<tspan style="font-size: 8.75px; " x="0" y="0">∗</tspan>
</text>
<text transform="matrix(1,0,0,-1,-66.87,62.83)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑃</tspan>
<tspan style="font-size: 12.50px; " x="10.890113" y="0">&lt;</tspan>
<tspan style="font-size: 12.50px; " x="22.930502" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="29.182001" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="32.307751" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="38.559254" y="0">5</tspan>
</text>
</g>
</g>
</svg>, comparison with nonneoplastic brain tissues; <svg height="11.9" id="M12" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 76.025002 11.9" width="76.025002" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,11.9)">
<g transform="translate(72,-62.48)">
<text transform="matrix(1,0,0,-1,-71.95,67.83)">
<tspan style="font-size: 8.75px; " x="0" y="0">∗</tspan>
<tspan style="font-size: 8.75px; " x="4.5772958" y="0">∗</tspan>
</text>
<text transform="matrix(1,0,0,-1,-62.3,62.83)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑃</tspan>
<tspan style="font-size: 12.50px; " x="10.890113" y="0">&lt;</tspan>
<tspan style="font-size: 12.50px; " x="22.930502" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="29.182001" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="32.307751" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="38.559254" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="44.810753" y="0">1</tspan>
</text>
</g>
</g>
</svg>, comparison with nonneoplastic brain tissues.</table>

BioMed Research International

fig3

Figure 3

Figure 3: Aberrant Expression of N-Methylpurine-DNA Glycosylase Influences Patient Survival in Malignant Gliomas 