Effectiveness of Myocardial Contrast Echocardiography Quantitative Analysis during Adenosine Stress versus Visual Analysis before Percutaneous Therapy in Acute Coronary Pain: A Coronary Artery TIMI Grading Comparing Study

Table 4

Comparison of myocardial perfusion parameters at rest and stress among TIMI flow grades.

Myocardial perfusion parameters	TIMI flow grades
	Grade 0	Grade 1	Grade 2	Grade 3	W ^*	𝑃
A (db):
rest	1.06 ± 0.02^*§†	3.17 ± 0.08^*§	4.49 ± 0.32^*	5.29 ± 0.47	382.13	.000
stress	1.01 ± 0.06^*§†	3.09 ± 0.11^*§	4.83 ± 0.09^*＃	5.71 ± 0.53^*	499.64	.000
β (s−1):
rest	0.13 ± 0.02^*§†	0.17 ± 0.03^*§	0.24 ± 0.03^*	0.28 ± 0.01	192.61	.000
stress	0.11 ± 0.06^*§†	0.23 ± 0.05^*§#	0.57 ± 0.04^*#	0.71 ± 0.09^*	318.15	.000
A ×  β (db/S):
rest	0.14 ± 0.01^*§†	0.54 ± 0.03^*§	1.08 ± 0.02^*	1.39 ± 0.04	450.96	.000
stress	0.11 ± 0.01^*§†	0.71 ± 0.01^*§#	2.75 ± 0.09^*#	4.05 ± 0.11^*	601.17	.000
A-reserve	0.95 ± 0.08^*§†	0.98 ± 0.07^*§	1.08 ± 0.07^*	1.09 ± 0.05	452.14	.000
β-reserve	0.85 ± 0.02^*§†	1.36 ± 0.02^*§	2.37 ± 0.03^*	2.54 ± 0.05	267.82	.000
A ×  β-reserve	0.79 ± 0.02^*§†	1.31 ± 0.03^*§	2.55 ± 0.06^*	3.11 ± 0.05	539.74	.000

A: indicates myocardial blood volume; β: myocardial blood flow velocity; A ×  β: myocardial blood flow; A-reserve: stress A/rest A; β-reserve: stress β/rest β; A ×  β-reserve: stress A ×  β/rest A ×  β;  TIMI: thrombolysis in myocardial infarction trial.
The correlation between the means of A, β, and A ×  β at rest and TIMI grade reached significant (rs  =  0.741, 0.528, and 0.715, resp., 𝑃 values <.001).
The correlation between the means of A, β, and A ×  β at stress and TIMI grade reached significant (rs  =  0.872, 0.767, and 0.845 for A, β, and A ×  β, resp., 𝑃 values <.001).
^*𝑃<.001 versus TIMI grade 3.
^§𝑃<.001 versus TIMI grade 2.
^†𝑃<.001 versus TIMI grade 1.
^#𝑃<.001 versus parameter in rest.
^*Welch tests.