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Journal of Biomedicine and Biotechnology
Volume 2012, Article ID 808762, 4 pages
Research Article

The Effect of Tinospora crispa on Serum Glucose and Insulin Levels in Patients with Type 2 Diabetes Mellitus

Department of Medicine, Ramathibodi Hospital, Faculty of Medicine, Mahidol University, Bangkok 10400, Thailand

Received 27 July 2011; Revised 15 August 2011; Accepted 25 August 2011

Academic Editor: Masa-Aki Shibata

Copyright © 2012 Theerawut Klangjareonchai and Chulaporn Roongpisuthipong. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. W. Aekplakorn, R. P. Stolk, B. Neal et al., “The prevalence and management of diabetes in Thai adults: the International Collaborative Study of Cardiovascular Disease in Asia,” Diabetes Care, vol. 26, no. 10, pp. 2758–2763, 2003. View at Publisher · View at Google Scholar · View at Scopus
  2. S. S. Ajgaonkar, “Herbal drugs in the treatment of diabetes mellitus,” International Diabetes Federation Bulletin, vol. 24, pp. 10–19, 1979. View at Google Scholar
  3. H. Noor and S. J. H. Ashcroft, “Antidiabetic effects of Tinospora crispa in rats,” Journal of Ethnopharmacology, vol. 27, no. 1-2, pp. 149–161, 1989. View at Publisher · View at Google Scholar · View at Scopus
  4. H. Noor and S. J. H. Ashcroft, “Pharmacological characterisation of the antihyperglycaemic properties of Tinospora crispa extract,” Journal of Ethnopharmacology, vol. 62, no. 1, pp. 7–13, 1998. View at Publisher · View at Google Scholar
  5. C. Sangsuwan, S. Udompanthurak, S. Vannasaeng, and V. Thamlikitkul, “Randomized controlled trial of Tinospora crispa for additional therapy in patients with type 2 diabetes mellitus,” Journal of the Medical Association of Thailand, vol. 87, no. 5, pp. 543–546, 2004. View at Google Scholar · View at Scopus
  6. N. Kongkathip, P. Dhumma-upakorn, B. Kongkathip, K. Chawananoraset, P. Sangchomkaeo, and S. Hatthakitpanichakul, “Study on cardiac contractility of cycloeucalenol and cycloeucalenone isolated from Tinospora crispa,” Journal of Ethnopharmacology, vol. 83, no. 1-2, pp. 95–99, 2002. View at Publisher · View at Google Scholar · View at Scopus
  7. C. Sriyapai, R. Dhumma-upakorn, S. Sangwatanaroj, N. Kongkathip, and S. Krittiyanunt, “Hypoglycemic effect of tinospora crispa dry powder in outpatients with metabolic syndrome at king chulalongkorn memorial hospital,” Journal of Health Research, vol. 23, no. 3, pp. 125–133, 2009. View at Google Scholar · View at Scopus
  8. H. Noor, P. Hammonds, R. Sutton, and S. J. H. Ashcroft, “The hypoglycaemic and insulinotropic activity of Tinospora crispa: studies with human and rat islets and HIT-T15 B cells,” Diabetologia, vol. 32, no. 6, pp. 354–359, 1989. View at Google Scholar · View at Scopus
  9. N. Kongkathip, S. Jnakana, B. Kongkathip et al., “Extraction and purification of hypoglycemic agent from Tinospora Crispa,” Final report, Bangkok: Department of Chemistry, Faculty of Science, Kasetsart University, 2006.