Administration of Bone Marrow Derived Mesenchymal Stem Cells into the Liver: Potential to Rescue Pseudoxanthoma Elasticum in a Mouse Model (<i>Abcc6<sup>−/−</sup></i>)

<table>Schematic depiction of liver targeting of MSCs through intrasplenic injection. GFP-transgenic mouse bone marrow derived MSCs, which are positive for GFP, Sca-1, Cxcr4, and <i>Abcc6</i>, were injected through spleen 24 hours after partial hepatecotomy inducing release of SDF-1, a ligand of Cxcr4. The presence of transplanted cells was observed by a live imaging system at day 7 posttransplantation through ventral view (liver) and dorsal view (spleen).</table>

BioMed Research International

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Figure 8

Figure 8: Administration of Bone Marrow Derived Mesenchymal Stem Cells into the Liver: Potential to Rescue Pseudoxanthoma Elasticum in a Mouse Model (<i>Abcc6<sup>−/−</sup></i>) 

Figure 8 | Administration of Bone Marrow Derived Mesenchymal Stem Cells into the Liver: Potential to Rescue Pseudoxanthoma Elasticum in a Mouse Model (Abcc6−/−) 