Review Article

Acid-Base Disorders in Patients with Chronic Obstructive Pulmonary Disease: A Pathophysiological Review

Figure 2

Cellular mechanism for ammoniagenesis and NH4ā€‰+ secretion. NH3 can be secreted into the tubular fluid, where it is then protoned, or it can bind H+ within the cell, and be secreted as ammonium ion.
915150.fig.002