The Inhibitory Effect of Prunella vulgaris L. on Aldose Reductase and Protein Glycation

Table 1

Inhibitory effects of the P. vulgaris L. on rat lens aldose reductase (rAR).

Fraction	Concentration (𝜇g/mL)	Inhibition (%)	IC50 (𝜇g/mL)
	10	75.33 ± 0.55
Quercetin^a	5	64.72 ± 1.56	1.53 ± 0.16
	1	44.7 ± 1.39
Water extract	10	36.18 ± 1.13	—
n-Hexane fr.	10	33.94 ± 0.49	—
Methylene chloride fr.	10	32.49 ± 0.54	—
	10	87.33 ± 2.39
Ethyl acetate fr.	5	62.79 ± 1.48	2.99 ± 0.10
	1	18.34 ± 0.59
n-Butanol fr.	10	59.56 ± 2.34	—
Water fr.	10	—	—

Inhibition rates were calculated as percentages with respect to the control value. ^aQuercetin was used as positive control. Inhibitory effect was expressed as mean ± SD of triplicate experiments.