Table 2: Effects of ginsenoside Rb1 on angiogenesis from the area surrounding burn wounds in mice [26].

TreatmentBlood vessel length (mm/field)Blood vessel area (mm2/field)

Untreated burn wounds (control) 7 5 . 6 ± 2 4 . 9 1 0 . 5 ± 3 . 8

+Ginsenoside Rb1
 (100 fg/wound) 2 2 8 . 8 ± 3 8 . 6 * 4 6 . 6 ± 1 5 . 0 *
 (10 pg/wound) 2 0 3 . 0 ± 1 7 . 0 * 3 7 . 6 ± 5 . 5 *
 (1 ng/wound) 2 7 4 . 1 ± 3 7 . 4 * 4 9 . 9 ± 4 . 7 *

+bFGF 2 4 1 . 5 ± 2 8 . 3 * 3 5 . 8 ± 5 . 9 *

The burn wounds were created on the backs of male Balb/c mice (6 weeks old) under anesthesia with pentobarbital. A polyethylene filter pellet (about 8 mm in diameter, 3 mm thick) containing the indicated amount of basic fibroblast growth factor (bFGF) or ginsenoside Rb1 was applied to the burn wound surface. On day 9, any angiogenesis in the site surrounding the burn wound was photographed using a stereoscopic microscope, and the area and length of blood vessels were measured using a Coordinating Area and Curvimeter Machine (X-PLAN 360 dII, Ushitaka, Tokyo, Japan).
Values are the mean ± SE for six mice. *Significantly different from untreated burn wounds (control), 𝑃 < 0 . 0 5 .