Depigmenting Effect of Kojic Acid Esters in Hyperpigmented B16F1 Melanoma Cells

Table 3

Antioxidant effects of KA, KAMP, KAML and KAMO using DPPH. Denotes ^∗𝑃<0.05, ^∗∗𝑃<0.01, ^∗∗∗𝑃<0.001 compared to untreated control. Data are presented as means ± S.E.M, and expressed as % of control, 𝑛≥3.

Sample	Concentration (μg/mL)	Scavenging activity (% of control) S.E.M
Control	0	0.06 ± 0.06
KA	1.95	5.86 ± 0.28^***
	62.5	29.24 ± 4.18^*
	250	46.73 ± 5.21^*
	1000	57.07 ± 1.64^***
KAMP	1.95	3.00 ± 0.40^*
	62.5	4.69 ± 0.34^**
	250	9.41 ± 3.43
	1000	53.05 ± 13.47^*
KAML	1.95	3.28 ± 3.14
	62.5	11.96 ± 9.61
	250	16.91 ± 5.06
	1000	44.70 ± 6.66^*
KAMO	1.95	17.44 ± 3.24^*
	62.5	24.54 ± 2.89^**
	250	35.20 ± 1.41^**
	1000	59.01 ± 2.89^**
L-ascorbic	62.5	48.73 ± 3.84^***