Enhanced Hemostatic Performance of Tranexamic Acid-Loaded Chitosan/Alginate Composite Microparticles

Table 1

The hemostatic efficiency of several materials for the hepatic hemorrhage model of rabbits.

	Weight of resected liver (g)	Total blood loss (g/kg)	Bleeding time (min)
Flashclot	1.98 ± 0.22	1.61 ± 0.83	3.07 ± 0.84
Composite particle	1.93 ± 0.27	1.27 ± 0.47	2.48 ± 0.88
Tranexamic acid-loaded particle	1.84 ± 0.21	1.32 ± 0.63	1.90 ± 0.75^Δ*

^Δ𝑃<0.01 compared with Flashclot, ^∗𝑃<0.05 compared with composite powder.