1,25-Dihydroxyvitamin D3 Inhibits the RANKL Pathway and Impacts on the Production of Pathway-Associated Cytokines in Early Rheumatoid Arthritis

Table 1

The serum levels of RANKL, OPG, and associated cytokines in RA patients versus control group.

	RANKL; (pmol/L)	OPG; (pmol/L)	RANKL/OPG	TNF-𝛼; (pg/mL)	IL-17; (pg/mL)	IL-6; (pg/mL)	IL-4; (pg/mL)
RA group	100.17 ± 22.27	0.64 ± 0.17	169.57 ± 59.38	5.91 ± 2.53	42.56 ± 6.43	16.63 ± 12.00	2.72 ± 0.36
Healthy control group	75.82 ± 9.108	0.53 ± 0.16	149.00 ± 26.71	2.63 ± 0.27	21.10 ± 3.22	4.16 ± 2.27	2.72 ± 0.33

Values are expressed as mean ± standard deviation.