Extending the Serum Half-Life of G-CSF via Fusion with the Domain III of Human Serum Albumin
Figure 6
In vivo bioactivity of the purified 3DHSA-G-CSF. Both G-CSF and 3DHSA-G-CSF could increase the white blood cell counts in a cyclophosphamide-induced neutropenia model murine, and more potent stimulate was observed compared with CTX (). G-CSF versus 3DHSA-G-CSF not significant (ns) (). Values are expressed as mean ± SD among six samples from one experiment. Data are representative of three independent experiments with similar result.
