Review Article

Children with Generalised Joint Hypermobility and Musculoskeletal Complaints: State of the Art on Diagnostics, Clinical Characteristics, and Treatment

Table 3

Critical appraisal of included study designs, risk of bias.

Items  Remarks
Treatment allocationBlindingLoss to follow-up

Total score
StudyEligibility
criteria
RandomizedConcealed
allocation
Baseline
comparability
SubjectsTherapistsAssessorsMeasures obtained in 85% of all initially included subjectsIntention to treatGroup
comparison reported
Point measures and
measures of variability reported

van Brussel et al.,
(2008) [73]
YesYesYesYes1NoNoYesYesYesYesYes8/10 1Corrections were applied

Mintz-Itkin et al.,
(2009) [61]
YesNo2No2YesNoNoNoNo3NoYesYes3/10 2No randomization method was specified
3No data on loss to follow-up was presented

Kemp et al.,
(2009) [59]
YesYesYesYes4NoNo3NoNoYesYesYes6/10 3Therapists were blinded for disease characteristics
4No formal statistical data was presented in which baseline comparability was ascertained