Effect of Mesenchymal Stem Cells and a Novel Curcumin Derivative on Notch1 Signaling in Hepatoma Cell Line

<table>Comparison between MTT proliferation assays of HepG2 cells. *Values differ significantly from HepG2 control cells. <svg height="14.8" id="M17" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 7.7375002 14.8" width="7.7375002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.012,-0,0,-.012,.062,6.587)"><path d="M574 0h-62l-217 479h-2l-217 -479h-62l249 548h62z" id="x2227"></path></g>
</svg>Values differ significantly from HepG2+MSC CM. <sup>#</sup>Values differ significantly from HepG2+NCD.  <svg height="16.525" id="M18" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 9.2875004 16.525" width="9.2875004" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.012,-0,0,-.012,2.9,8.313)"><path d="M264 363l29 -11q141 -51 141 -167q0 -71 -45.5 -117.5t-124.5 -56.5v-87h-35v85q-93 0 -156 41q-11 32 -28 132l30 8q41 -135 154 -148v242l-36 16q-126 54 -126 153q0 62 42.5 107.5t119.5 54.5v78h35v-76q50 0 89 -13q6 -1 17 -4t17 -4l10 -60.5l11 -64.5l-28 -7
q-16 53 -39 82.5t-77 37.5v-221zM229 376v208q-45 -4 -69 -33t-24 -67q0 -72 93 -108zM264 272v-229q45 6 70 35.5t25 71.5q0 39 -17.5 67t-65.5 50z" id="x24"></path></g>
</svg>Values differ significantly from HepG2 cells+MSC CM, (MSCs pretreated with NCD).</table>

BioMed Research International

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Figure 4

Figure 4: Effect of Mesenchymal Stem Cells and a Novel Curcumin Derivative on Notch1 Signaling in Hepatoma Cell Line 