Research Article
In Vitro Release Kinetics of Antituberculosis Drugs from Nanoparticles Assessed Using a Modified Dissolution Apparatus
Table 2
Kinetic assessment of release data of MX-Gel-NPs in diverse buffers (
).
| Methods | Media | Korsmeyer-Peppas | | |
| Modified cylinder method | pH 7.4 | 0.3640 | 0.9956 | pH 4.0 | 0.2538 | 0.9765 | pH 1.2 | 0.2944 | 0.9631 | pH 7.4-trypsin | 0.6918 | 0.9503 | pH 4.0-trypsin | 0.6910 | 0.9979 | pH 1.2-trypsin | 0.8966 | 0.9780 |
| Dialysis bag technique | pH 7.4 | 0.3032 | 0.9875 | pH 4.0 | 0.1899 | 0.9893 | pH 1.2 | 0.2891 | 0.9863 | pH 7.4-trypsin | 0.3902 | 0.9825 | pH 4.0-trypsin | 0.2678 | 0.9824 | pH 1.2-trypsin | 0.3614 | 0.9122 |
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Diffusional exponent and squared correlation coefficient.
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