Clinicopathological Impact of ABCC1/MRP1 and ABCC4/MRP4 in Epithelial Ovarian Carcinoma

Table 1

Patient’s clinical characteristics.

Characteristics	Patients (𝑛=127)
	N°	%
Age, years
(mean, median 58; range 23–84)
Tumor histotype
Serous	83	65
Undifferentiated	12	10
Clear cell	12	10
Endometrioid	12	10
Mucinous	6	4
Others + mixed	2	1
Tumor stage (FIGO)
I	24	19
II	15	12
III	64	50
IV	23	18
Not available	1	1
Tumor grade
1: well differentiated	9	7
2: moderately differentiated	48	38
3: poorly differentiated	53	42
Undifferentiated	12	10
Not available	5	3
Amount of residual disease
NED	47	37
<1 cm	19	15
>1 cm	46	36
Not available	15	12
Frontline treatment
None	8	6
Platinum without taxanes	81	64
Platinum/paclitaxel	35	28
Other or not available	3	2
Response to frontline treatment*
Complete	57	46
Partial	21	18
No response	21	18
Not available	21	18

Abbreviations: FIGO: International Federation of Gynecological and Obstetrics staging system. NED: not evident disease. ∗Untreated patients are not included.