S100A12 and hBD2 Correlate with the Composition of the Fecal Microflora in ELBW Infants and Expansion of E. coli Is Associated with NEC

Table 2

Intestinal microflora in infants with NEC.

	96 to 120 h prior to NEC (𝑁=12)	Within 24 h of onset of NEC (𝑁=11)	P value
MEDIAN LOG10 CFU per g at day 7
Total bacterial count	9 (8.4–10.4)	9.9 (9.4–10.6)	0.04
Lactobacilli	8.7 (7.8–10.5)	8.9 (8.6–9.2)	0.49
C. difficile (if positive)	6.3 (4.4–8.3)	6.7 (4.1–9.3)	0.46
E. coli	7.9 (5.1–8.1)	9.5 (8.8–10.3)	<0.001
Bifidobacteria	7.5 (5.1–7.6)	8.3 (6.7–9.2)	0.11
B. fragilis group	5.8 (5.6–6.3)	7.0 (6.6–7.3)	0.28
Others	8.6 (7.7–9.9)	9.1 (8.4–9.5)	0.44
Prevalence of C. difficile (N)	33.3% (4)	27.2% (3)