Review Article

Topical Promethazine Side Effects: Our Experience and Review of the Literature

Table 1

PM clinical use.

Common useOther less common uses

Drug hypersensitivity reactions
Allergic conditions in emergencies
Asthma, pneumonia
Other lower respiratory tract infections
Nasal sleep-introducing drug
Anaesthetic premedication, particularly in obstetrics
To reduce postoperative nausea and vomiting particularly in obstetrics
To prevent motion sickness
As a cough-relieving medicament for treating inflammation, allergy, and autoimmune conditions
For the reduction of intracranial pressure
Antipruritic relief to patients
For the treatment of neoplastic disorders
Sperm-killing effect
To inhibit the decomposition of hyaluronic acid
As a melanogenesis-suppressing agent
For treating haemorrhoids
To control extrapyramidal disorders in children
To produce sedation in dental procedures in children
As a 2% cream for allergic skin conditions, insect bites, and burns