Human Mesenchymal Stem Cells Provide Protection against Radiation-Induced Liver Injury by Antioxidative Process, Vasculature Protection, Hepatocyte Differentiation, and Trophic Effects
Human β-2-microglobulin immunostaining in mouse liver, 30 days after TBI. And percentage of mouse livers engrafted with hMSCs from 3 to 60 days after TBI. Immunostaining of hepatic cells (b), endothelium of portal vein (d) with human cells expressing beta-2-microglobulin stained in red, and respective negative controls ((a) and (c)). Isolated human cells can be seen between hepatic ((b) black arrow) and endothelial cells ((d) black arrow). (e) Negative control nonirradiated, noninjected with hMSCs (f).
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