LRP-1: A Checkpoint for the Extracellular Matrix Proteolysis

Table 1

Main matrix proteinases and specific inhibitors known to bind to LRP-1.

Serine proteinases, serpins, and serine proteinase/serpin complexes
tPA	PAI-1	tPA, uPA/PAI-1
(pro)uPA		uPA/PAI-2
MMPs, TIMPs, and MMP/TIMP complexes
(pro)MMP-2/TSP-1, -2	TIMP-1	(pro)MMP-2/TIMP-2; (pro)MMP-9/TIMP-1
(pro)MMP-9	TIMP-2
(pro)MMP-13	TIMP-3
Other matrix proteinases
Heparanase precursor
Procathepsin-D
ADAMTS-5