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BioMed Research International
Volume 2013 (2013), Article ID 154919, 10 pages
Research Article

Effect of Ex Vivo Culture Conditions on Immunosuppression by Human Mesenchymal Stem Cells

1Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University College of Medicine, 50 Irwon-dong, Gangnam-gu, Seoul 135-710, Republic of Korea
2Biomedical Research Institute, LIFELIVER. Co., LTD., 877-3 Jukjeon-dong, Suji-gu, Yongin-si, Gyeonggi-do 448-807, Republic of Korea
3Department of Pediatrics, Dong-A Medical Center, Dong-A University College of Medicine, 26 Daesingongwonro, Soe-gu, Busan 602-172, Republic of Korea

Received 7 January 2013; Revised 20 March 2013; Accepted 16 April 2013

Academic Editor: Wolfgang Arthur Schulz

Copyright © 2013 Myoung Woo Lee et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Table: List of genes that were differentially expressed in MSCs harvested at high cell confluence and at low cell confluence. Among the 24,526 genes analyzed, 276 genes were more highly expressed in MSCs harvested at ∼90% (CC3 MSCs) versus ∼50% confluence (CC1 MSCs), whereas 230 genes were down-regulated (P < 0.05, Fold Change > 2).

  1. Supplementary Table